TABLE 4 : CLASSIFICATION OF TRANSFUSION

REACTIONS ( This is not an exhaustive list )

IMMUNE-MEDIATED TRANSFUSION REACTIONS

Constituent                                 Type of Reaction

Red Cells                       Acute hemolytic transfusion reactions

                                       Delayed hemolytic transfusion reactions

                                       Alloimmunization to red cell antigens

White Cells                    Febrile transfusion reactions

                                       Pulmonary edema

                                       Alloimmunization to white cell antigens

Platelets                         Alloimmunization to platelet-associated antigens

                                       Post transfusion purpura

Plasma Proteins             Urticaria

                                       Anaphylaxis

Lymphocytes                 Graft-versus-host disease

NON-IMMUNE TRANSFUSION REACTIONS

Category                                      Type of Reaction

Disease                         Hepatitis B

Transmisission             Hepatitis C (non-A , non-B)

                                     Cytomegalovirus disease (CMV)

                                     Malaria

                                     AIDS

                                     Syphilis

Septicemia                   Bacterial sepsis due to the infusion of infected

                                     blood products

Embolism                     Air embolism

                                     Microembolism

Overload                      Fluid overload

                                     Electrolyte imbalance

                                     Iron overload

                                     Citrate overload

Hemorrhagic                Thrombocytopenia

Diathesis                      Coagulation factor deficiencies

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